Austin Pathology

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Neuronal Antibodies - Cerebrospinal Fluid (CSF)

Alternate Names
Paraneoplastic Antibodies, ANNA-1, Anti-Hu, ANNA-2, Anti-Ri, Anti-PCA-1, Anti-Yo, Anti-PCA-2, Anti-CV2, CRMP5, Anti-PCA-Tr, Anti-Ma, Anti-Ta, Anti-GAD, Anti-amphiphysin, Anti-DPPX, DPPX
Ordering Information

If specific neuronal antibodies are desired, please specify these on the request form. Otherwise, general requests will be screened for most common antibodies.

Screening for neuronal antibodies will be performed via indirect immunofluorescence. If screening is positive, additional specificities will be performed (see below):

  • ANNA-1/anti-Hu
  • ANNA-2/anti-Ri
  • Anti-PCA-1/anti-Yo
  • Anti-PCA-2
  • Anti-CV2/CRMP5
  • Anti-PCA-Tr
  • Anti-Ma/Ta
  • Anti-GAD
  • Anti-amphiphysin
  • Anti-DPPX
Laboratory
Referred Test
Specimen
CSF
Container
Sterile CSF tube
Additional Collection Instructions

CSF samples should be sent to the laboratory immediately. Ensure all caps are screwed on correctly to avoid leakage.

Minimum Adult Volume
None
Minimum Paediatric Volume
None
Frequency
Monthly
Reference Interval

This test is not performed in-house. Refer to reference interval on results report.

Test Code
NEURAB
Container ID
CSF4,CSF1,CSF2,CSF3,CR,CRS,CB,CBS
Storage Instructions
Store frozen at -20°C
Transport Instructions
Transport frozen
Laboratory Notes

Instructions for: Metropolitan & Regional Specimen Receptions

CSF samples should be handled urgently.

Where there are multiple tubes from a lumbar puncture:

  • Tube 3 is for Microbiology and 1, 2 for Biochemistry, Cytology, etc. (If tube 3 is not available for Microbiology, send tube 2)
  • If tap is traumatic (blood-stained), 1 and 3 go to Microbiology for cell counts.

 If insufficient tubes are received for the tests requested, please contact the Medical Microbiologist or Registrar

External Laboratory
Immunology, Royal Brisbane & Women's Hospital