Austin Pathology

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Anti-Neuronal Antibodies (Blood)

Alternate Names
Anti Neuronal Antibodies, Paraneoplastic Antibodies, ANNA-1, Anti-Hu, ANNA-2, Anti-Ri, Anti-PCA-1, Anti-Yo, Anti-PCA-2, Anti-CV2, CRMP5, Anti-PCA-Tr, Anti-Ma, Anti-Ta, Anti-GAD, Anti-amphiphysin, Anti-DPPX, DPPX, Neuronal Ab, Neuronal Ab Tr
Test Code
NEURAB
Testing Laboratory
Referred Laboratory
Specimen Type

Blood

Container Type

Serum tube (Red Cap w. Yellow Insert)

Container Image
Medicare Rebate

Yes

Out of Pocket Costs
None
Ordering Information

If specific neuronal antibodies are desired, please specify these on the request form. Otherwise, general requests will be screened for most common antibodies.

Screening for neuronal antibodies will be performed via indirect immunofluorescence. If screening is positive, additional specificities will be performed (see below):

  • ANNA-1/anti-Hu
  • ANNA-2/anti-Ri
  • Anti-PCA-1/anti-Yo
  • Anti-PCA-2
  • Anti-CV2/CRMP5
  • Anti-PCA-Tr
  • Anti-Ma/Ta
  • Anti-GAD
  • Anti-amphiphysin
  • Anti-DPPX

Note: This test is strongly advised to be performed on both CSF and serum to optimise sensitivity and specificity. Consider combining with Autoimmune Encephalitis Screen testing if indicated.

Collection Instructions

-

Transport Instructions
Transport ambient at room temperature
Storage Instructions
Store refrigerated at 4°C
Testing Frequency
Monthly
Min Test Volume
2mL
Add On Test Suitability
Refrigerated (2 - 4°C)

up to 3 months*

Frozen Plasma (-20°C) up to 3 months*

 

*Subject to sample availability

Container ID
S,SP
CSR Instructions

Centrifuge, aliquot, and freeze AS SOON AS POSSIBLE.

Instructions for: Regional Specimen Receptions

  • Forward sample to Heidelberg laboratory frozen in BioFreeze bottle. 

Instructions for: Heidelberg Specimen Reception

  • Place sample in frozen (-20°C) Sendout tub.
  • If a room temperature or 4°C sample is received, it can still be accepted. 
  • Create an aliquot for freezing.
  • If a room temperature or 4°C sample is received from a regional laboratory, ensure it is received from the frozen packing list.
Laboratory Instructions
None
External Laboratory
Immunology, Royal Brisbane & Women's Hospital
Accredited Test
Yes