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Autoimmune Encephalitis (CSF)

Alternate Names
-
Test Code
NMDA, GABA, AMPA, LGI1, CASPR2
Testing Laboratory
Referred Laboratory
Specimen Type

CSF
Container Type

Sterile CSF Tube
Medicare Rebate

No - please complete Patient Financial Consent Form.pdf

Out of Pocket Costs

Please note: Some tests are not Medicare rebatable and patients may be charged. Please contact Pathology Queensland for current pricing (07 3646 5811)
Ordering Information

Ordering this test results in ordering all Autoimmune Encephalitis antibodies, which are NMDA, GABA, AMPA, LGi1, CASPR2 antibodies.

For specific antibodies, please refer to the pages below: 

If VGKC antibody is requested on a CSF sample this will result in LGi1 and CASPR2 antibodies being ordered. 

Note: This test is strongly advised to be performed on both CSF and serum to optimise sensitivity and specificity. Consider combining with Anti Neuronal Antibodies testing if indicated.
Collection Instructions

CSF samples should be sent to the laboratory immediately. Ensure all caps are screwed on correctly to avoid leakage & sterility. 
Transport Instructions
Transport ambient at room temperature
Storage Instructions
Store refrigerated at 4°C
Testing Frequency
As Required
Min Test Volume
None
Add On Test Suitability
Refrigerated (2-4°C) up to 3 months*
Frozen (-20°C) up to 3 months*


*Subject to sample availability
Container ID
CSF1, CSF2, CSF3, CSF4, CR
CSR Instructions

Instructions for: Metropolitan and Regional Specimen Receptions

  • If VGKC Antibody is ordered on a CSF sample, please code for LGI1 and CASPR2. 
  • If only a CSF specimen is received, organise an additional serum collection. 

Instructions for: Regional Specimen Receptions

  • Forward specimens frozen to the Heidelberg laboratory.
Laboratory Instructions

Instructions for: Metropolitan & Regional Specimen Receptions 

CSF samples should be handled urgently. 

Where there are multiple tubes from a lumbar puncture: 

  • Tube 3 is for Microbiology and 1, 2 for Biochemistry, Cytology, etc. (If tube 3 is not available for Microbiology, send tube 2) 
  • If tap is traumatic (blood-stained), 1 and 3 go to Microbiology for cell counts. 

If insufficient tubes are received for the tests requested, please contact the Medical Microbiologist or Registrar (03 9496 5964
External Laboratory
Immunology, Royal Brisbane & Women's Hospital
Accredited Test
Yes

These PDF documents can be downloaded for your reference

Order of Draw (PDF)

Swab Collection Guide (PDF)

Pre-Transfusion Specimen Requirements (PDF)

Requirements for Pathology Service (PDF)

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Austin Hospital Studley Road
Heidelberg, VIC 3084
Phone:9496-3100
Fax: 03 9496 5803

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