Colorectal Carcinoma NGS Panel (Tissue) Test | Austin Pathology

Our hours are changing over the holiday period. View our Christmas Closures PDF for up-to-date information.

Austin Pathology

Test Directory

Search in the bar above for available tests.
Type any letter of the alphabet to be presented with all available results for that letter.

Colorectal Carcinoma NGS Panel (Tissue)

Alternate Names	KRAS for colorectal, AKRAS, KRAS for solid tumour, KRAS for CRC
Test Code	ESTNGS
Testing Laboratory	Molecular Diagnostics - Genetics
Specimen Type	Tissue
Container Type	Glass slides Tumour Block
Medicare Rebate	Yes
Out of Pocket Costs	Please note: Medicare Rebate for this test is subject to conditions. Patients may receive an invoice. Out of Pocket cost: Colorectal Carcinoma NGS Panel Gene list: APC, ARID1A, BRAF, CTNNB1, EPCAM, ERBB2, KRAS, MLH1, MSH2, MSH6, NRAS, PIK3CA, PMS2, POLE, SMAD4, TP53 MBS Item No. 73338 Non-Medicare eligible - $675.00 Fee above is an indication only; please contact testing laboratory for up-to date cost.
Ordering Information	Please refer to Molecular Genetics - Austin Pathology for specific testing details and request form for ordering. After this form has been completed, please forward it to the Anatomical Pathology laboratory via the fax number found on the request form. Mutations in KRAS is also investigated in the Myeloid NGS panel. This test is specifically for the investigations of KRAS mutation in solid tumours like colo-rectal cancer.
Collection Instructions	At least 10% tumour nuclei 5μm sections on uncoated slides - 7 sections for resection specimens OR 10 sections for small biopsies or resections with very focal tumour OR FFPE tissue block Copy of the histology or cytology report
Transport Instructions	Transport ambient at room temperature
Storage Instructions	Store refrigerated at 4°C
Testing Frequency	Weekly
Min Test Volume	25μm
Add On Test Suitability	Contact Molecular Diagnostics - Genetics on 03 9496 5657 to confirm add on suitability.

Container ID	CMOL, CMOLS, CFT, CC, HIS, POT
Laboratory Instructions	The Anatomical Pathology department will register the test, obtain the tissue block or slides (using the test code MOLA), and forward them to Molecular Diagnostics for testing. After testing, it will be registered as ESTNGS, and the relevant sub-panel will be added (including Lung, BRCA Tumour, CRC, Endometrial, Epilepsy, GIST, Glioma, Kidney, Bladder, Melanoma, MMR, Ovarian SCST, Ovarian Serous, Pancreas, Liver, Prostate, Thyroid & Solid Tumour (Full) NGS Panel) by selecting the option from the drop-down menu under the "Extended Solid Tumour NGS" tab of the ESTNGS test code
Accredited Test	Yes

These PDF documents can be downloaded for your reference

Order of Draw (PDF)

Swab Collection Guide (PDF)

Pre-Transfusion Specimen Requirements (PDF)

Requirements for Pathology Service (PDF)