Austin Pathology

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Oncogenic HPV and genotype detection by PCR (Thin Prep)

Alternate Names
HPV PCR, HPV test, HPV +/- (reflex LBC), Test of Cure, Co-Test, Proof of Cure
Test Code
THINP
Testing Laboratory
Molecular Diagnostics - Infectious
Specimen Type

Cervico-vaginal smears

Container Type

Thin Prep Preserve Cyt Vial

Medicare Rebate

Yes

Out of Pocket Costs
None
Ordering Information

This assay specifically identifies HPV genotypes 16 and 18 while concurrently detecting the other high risk genotypes (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68) at clinically relevant infection levels.

Currently this assay is only validated for diagnoses not screening purposes. For asymptomatic screening, please refer to: Cervical Screening Test - Clinician Collect.

Test of Cure

It is recommended that patients who have received treatment for a high-grade abnormality should complete Test of Cure surveillance to confirm their treatment has been successful. Test of Cure surveillance is a co-test (HPV PCR and Liquid Based Cytology) performed twelve months after treatment and annually thereafter, until the patient receives a negative co-test in two consecutive occasions. They should then return to five-yearly screening.

This assay is indicated when high grade dysplasia has been proven histologically and cytologically.

Co-Testing

Co-testing involves the pathology laboratory performing both the HPV PCR test and Liquid Based Cytology (LBC) concurrently on the same specimen. This means the LBC test is performed irrespective of the HPV test result, without requiring an additional request.

This assay is used for testing when patients present with symptoms such as post-coital bleeding.


This is only indicated on testing that is for cervico-vaginal specimens.

Samples for HPV PCR which are not Female Genitalia, please refer to Human Papilloma Virus PCR

Collection Instructions

THINPREP COLLECTION GUIDE

  • Plastic Spatula and Endocervical Brush


  • Cervical Sampler Broom


  • Broom and Endocervical Brush

 

Transport Instructions
Transport ambient at room temperature
Storage Instructions
Store refrigerated at 4°C
Testing Frequency
Weekly
Min Test Volume
None
Add On Test Suitability

This test can be added up to 4 weeks from collection. 

Container ID
CC, CCS
CSR Instructions

Instructions for: Heidelberg Specimen Reception

  • All samples are to be forwarded to Anatomical Pathology.
Laboratory Instructions
None
Accredited Test
Yes