Austin Pathology

Test Directory

Search in the bar above for available tests.
Type any letter of the alphabet to be presented with all available results for that letter.

NT-proBNP

Alternate Names
N Terminal pro-BNP, NTBNP, NT ProBNP
Ordering Information

This assay is performed in preference to BNP.

Laboratory
Biochemistry
Specimen
Blood
Container
Serum tube (gold top)
Minimum Adult Volume
None
Minimum Paediatric Volume
None
Frequency
As required
Reference Interval

For the diagnosis of chronic heart failure in non-acute onset, the recommended cut-off is 125 ng/L.

NTBNP less than 125ng/L Excludes cardiac dysfunction with a high level of certainty.
NTBNP greater than125ng/L May indicate cardiac dysfunction and increased risk of cardiac complications.

 

For the diagnosis of chronic heart failure in acute onset dyspnoea, the following cut-offs provide optimal sensitivity and specificity (ICON Study):

All ages NTBNP less than 300 ng/L:  RULE OUT HF
Less than 50 years old, NTBNP greater than 450 ng/L: RULE IN HF
50 – 75 years old, NTBNP greater than 900 ng/L: RULE IN HF
More than 75 years old, NTBNP greater than 1800 ng/L: RULE IN HF

Source: Roche Diagnostics