Austin Pathology

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Thyroid Function Tests

Alternate Names
TFT
Ordering Information

NOTE: For non-hospital requests, a TSH is the only test performed when a TFT is requested.

In the event that the TSH is greater than 5.0 mIU/L, a FT4 (and FT3 if TSH low) will be automatically added to the request.

If FT3 and/or FT4 are required up front, they must be specifically requested and be accompanied by clinical notes which satisfy one of the MBS requirements:

  • thyroid disease is being monitored
  • investigation of dementia
  • psychiatric illness; amenorrhoea
  • infertility
  • pituitary dysfunction
  • sick eurythoid syndrome 
  • patient is on medication/drugs that interfere with thyroid hormone metabolism or function.

 

As of 24/2/2020, TFT performed on Beckman-Coulter DxI. (Previous method: Roche e602). Please note reference intervals have been adjusted.

Laboratory
Biochemistry
Specimen
Blood
Container
Serum tube (gold cap OR red cap w. yellow insert)
Additional Collection Instructions

Can be combined with other Biochemistry tests requiring same tube type

Minimum Adult Volume
5mL
Minimum Paediatric Volume
1mL
Frequency
Daily
Reference Interval
  Age Reference Interval
TSH < 12 years 0.79 - 5.9 mU/L
12 - 19 years 0.68 - 3.4 mU/L
> 19 years 0.38 - 5.3 mU/L
FT4 < 20 days 17.4 - 57.7 pmol/L
20 days - 3 years 9.5 - 17.8 pmol/L
3 - 19 years 7.9 - 13.6 pmol/L
> 19 years 8.0 - 16.5 pmol/L
FT3 < 1 year 4.3 - 6.9 pmol/L
1 - 15 years 4.0 - 6.2 pmol/L
15 - 19 years (Female) 3.5 - 5.3 pmol/L
15 - 19 years (Male) 3.8 - 5.7 pmol/L
> 19 years 3.3 - 6.8 pmol/L

 

Thyroid Function Tests in Pregancy:

Beckman-Coulter trimester-specific reference intervals from McNeil AR. Clinical Biochem Rev 2015.

For gestations weeks less than 6, use non-pregnant reference intervals. Note: There are no Beckman-Coulter gestation-specific reference intervals for FT3.

 

  Trimester 1 (6 to less than 14 weeks) Trimester 2 (14 to less than 28 weeks) Trimester 3 (28 to 42 weeks)
TSH (mU/L) 0.12 - 3.12 0.29 - 3.51 0.25 - 3.93
FT4 (pmol/L) 7.6 - 14.7 6.0 - 12.5 5.3 - 11.6

Reviewed 12/08/2020