Austin Pathology

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Porphyrins - Urine

Alternate Names
PBG screen, Urine PBG
Referred Test
See collection instructions
See collection instructions
Collection Instruction
Collect at room temperature
Additional Collection Instructions

Specimen may be either a full MSU container of fresh urine (50 mL), or an aliquot of a 24 hour urine collection, no preservatives.

Wrap specimens in foil to protect from light and send to the laboratory immediately.

Minimum Adult Volume
Minimum Paediatric Volume
Urinary Porphyrins - Porphobilinogen Screen: A negative screen has been shown to correlate with porphobilinogen levels less than 10 µmol/L. 

Urinary Uro and Copro Porphyrin: Uroporphyrin and coproporphyrin levels in urine are usually calculated only when the total level is > 300 nmol/L.
Once a week
Reference Interval
Urine Creatinine 5 - 20 mmol/L
Porphobilinogen < 10 µmol/L
Total Porphyrins < 300 nmol/L
Porphyrin/Creatinine ratio < 35
Uroporphyrin < 40 nmol/L
Total Coproporphyrin < 150 nmol/L
Test Code
Storage Instructions
Store at 4 deg C
Transport Instructions
Transport at 4 deg C
External Laboratory
Biochemistry, Melbourne Health Shared Pathology Service