Austin Pathology

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Porphyrins - Urine

Alternate Names
PBG screen, Urine PBG
Laboratory
Referred Test
Specimen
See collection instructions
Container
See collection instructions
Collection Instruction
Collect at room temperature
Additional Collection Instructions

Specimen may be either a full MSU container of fresh urine (50 mL), or an aliquot of a 24 hour urine collection, no preservatives.

Wrap specimens in foil to protect from light and send to the laboratory immediately.

Minimum Adult Volume
50mL
Minimum Paediatric Volume
None
Notes
Urinary Porphyrins - Porphobilinogen Screen: A negative screen has been shown to correlate with porphobilinogen levels less than 10 µmol/L. 

Urinary Uro and Copro Porphyrin: Uroporphyrin and coproporphyrin levels in urine are usually calculated only when the total level is > 300 nmol/L.
Frequency
Once a week
Reference Interval
Urine Creatinine 5 - 20 mmol/L
Porphobilinogen < 10 µmol/L
Total Porphyrins < 300 nmol/L
Porphyrin/Creatinine ratio < 35
Uroporphyrin < 40 nmol/L
Total Coproporphyrin < 150 nmol/L
Test Code
UPOR
Storage Instructions
Store at 4 deg C
Transport Instructions
Transport at 4 deg C
External Laboratory
Biochemistry, Melbourne Health Shared Pathology Service