Patients with immune anti-D, anti-K or anti-c, must have a titration performed every 4 weeks until 28 weeks of pregnancy.  After 28 weeks, a titration should be performed every 2 weeks.  Clinical staff are responsible for ensuring repeat samples are sent when required.

Other antibody specificities (not anti-D, anti-c or anti-K) that have the possibility to cause HDFN require a titration upon initial identification of the antibody, or first presentation in the pregnancy if a known historical antibody, and at 28 weeks.  After 28 weeks no further antibody titrations are required.

Occasionally, an antibody titration may be requested (due to ultrasonic abnormalities or precious pregnancies) but is not normally indicated. This request must be discussed with a laboratory haematology consultant or registrar (9496 6206 or 9496 5981)

Specimen tube mandatory labelling criteria

• Surname AND given name
• Date of birth
• UR number and/or Address
• Date and time
• Sign or initial the specimen tube

Request for Blood/Blood Products form mandatory labelling criteria

• Surname AND given name
• Date of birth
• UR number and/or Address
• Date and time
• Complete and sign the request form declaration

All details including signatures and date/time on specimen tube and request form must match.

Handwritten details preferred. If a pre-printed label is used on the specimen, it MUST bear the collector's signature and date and time of collection.

Up to three red cell antigens are tested.